The story of a cancer-fighting molecule that took half a century to build is really a story about how slow, stubborn ...

Physicists have now demonstrated a particle accelerator so small it fits inside a single molecule, shrinking one of science’s most imposing machines to the scale of chemistry. Instead of ...

A version of this story appeared in Volume 103, Issue 11 Chemists and chemical biologists just keep dreaming up new ways to interfere with biomolecules. That research frequently leads to promising ...

Chemists offer two new methods to develop a way to easily replace a carbon atom with a nitrogen atom in a molecule. The findings could make it easier to develop new drugs. For years, if you asked the ...

From left: UChicago chemists Mark Levin, Jisoo Woo, and Tyler Pearson discuss techniques to swap nitrogen atoms in molecules—a change often made by drug discovery chemists. Credit: Julia Driscoll For ...

Scientists were able to manipulate a calcium monohydride molecular ion — made up of one atom of hydrogen and one atom of ...

A version of this story appeared in Volume 101, Issue 36 Not too long ago, these small-molecule drugs looked as if they were going out of fashion. Advances in biotechnology enabled pharmaceutical ...

There is more than one way to describe a water molecule, especially when communicating with a machine learning (ML) model, says chemist Robert DiStasio. You can feed the algorithm the molecule's ...

In a basement room at Austria's University of Graz sits a jumble of steel tanks and ice-encrusted tubes. The contraption, a scanning tunneling microscope, can snap pictures of individual atoms and ...

For years, if you asked the people working to create new pharmaceutical drugs what they wished for, at the top of their lists would be a way to easily replace a carbon atom with a nitrogen atom in a ...