The process of GLUT4 trafficking is central to the metabolic regulation of blood glucose levels. In both muscle and adipose cells, the insulin hormone triggers the mobilisation of intracellular ...

This is a preview. Log in through your library . Abstract Insulin-activated glucose transport depends on the efficient sorting of facilitated hexose transporter isoforms to distinct subcellular ...

Using high-resolution microscopy, researchers have shown how insulin prompts fat cells to take in glucose in a rat model. By studying the surface of healthy, live fat cells in rats, researchers were ...

The same powerful drugs that have extended the lives of countless people with HIV come with a price -- insulin resistance that can lead to diabetes and cardiovascular disease. Now, researchers have ...

This is a preview. Log in through your library . Abstract The functional trafficking steps used by soluble NSF attachment protein receptor (SNARE) proteins have been difficult to establish because of ...

How obesity feeds into insulin resistance remains somewhat of a mystery. A new study, which confined normal-weight men to hospital beds while having them consume 6,000 calories per day, sheds some ...

A study of the DNA of more than 55,000 people worldwide has shed light on how we maintain healthy blood sugar levels after we have eaten, with implications for our understanding of how the process ...

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Colon cancer risk is higher among type 2 diabetes patients Tests to identify the high risk group for colon cancer among diabetes patients can help in early diagnosis and treatment of the cancer ...

NIH/National Institute of Diabetes and Digestive and Kidney Diseases Using high-resolution microscopy, researchers at the National Institutes of Health have shown how insulin prompts fat cells to take ...