Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Type 2 diabetes has long been framed as a story of calories, weight and willpower, but a growing body of research is shifting ...

Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...

Study: Personalized molecular signatures of insulin resistance and type 2 diabetes. Image credit: Microgen/Shutterstock.com A recent study, published in the journal Cell, utilized cutting-edge ...

Scientists found that certain molecules made by gut bacteria travel to the liver and help control how the body uses energy.

Elevated fasting blood sugar and insulin levels, along with reduced insulin sensitivity, may predict cognitive impairment in MS patients. The study found significant correlations between cognitive ...

Chronic liver diseases tied to metabolic dysfunction—including metabolic dysfunction-associated steatotic liver disease (MASLD) and its more severe form, MASH—represent a rising global health crisis.

Obesity is not a single disease. New research shows distinct biological phenotypes that explain why weight gain and treatment ...