Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also ...

SINCE Lundsgaard showed that the contractile mechanism can work without production of lactic acid and that this acid, when formed, appears mainly, perhaps entirely, after contraction is over, the one ...

About EDG-5506 EDG-5506 is an orally administered small molecule designed to prevent muscle damage induced by mechanical stress in dystrophinopathies including DMD and BMD. EDG-5506 presents a novel ...

Researchers describe a new mechanism for muscle repair after physiological damage relying on the rearrangement of muscle fibre nuclei, and independently of muscle stem cells. Muscle is known to ...

Muscle thermodynamics; bioengineered muscle systems; molecular mechanisms of muscle contraction and regulation; mechanochemistry of molecular motor ensembles; single molecule and whole cell imaging; ...

A new study by researchers at Yale and Johns Hopkins University has discovered how asthmatic bronchial spasms — muscle contractions in the airway that cause difficulty breathing in asthma patients— ...

The mechanisms and physiological consequences of alternative splicing transitions during mammalian postnatal development The disruption of this regulatory network that is the pathogenic mechanism of ...

Cancer patients often lose excessive amounts of weight. This affects up to 80% of patients and is mainly due to a decrease in muscle mass and fatty tissue. This cancer-induced cachexia (CIC) is ...

Researchers have just made the unexpected discovery of a novel organization of muscle fibers in Parophidion vassali, a fish that lives in the Mediterranean Sea and, like many fish, uses specialized ...

Muscle is known to regenerate through a complex process that involves several steps and relies on stem cells. Now, a new study led by researchers at Pompeu Fabra University (UPF, Spain)/Centro ...