Allogene Therapeutics has dropped the bulk of a cell therapy collaboration with Notch Therapeutics, leaving just one chimeric antigen receptor (CAR) target from the original deal. Allogene tapped the ...

Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis. The Notch signaling pathway is integral to various cellular ...

Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis. The Notch signaling pathway is integral to various cellular ...

Sunitinib therapy for metastatic melanomas with KIT aberrations. Background: Treatment of metastatic melanoma remains a challenge because most cases are refractory to chemotherapy. The lack of ...

Signal transduction is the process through which a cell responds to external stimuli by altering the expression of its genes. Such systems typically function through downstream signaling cascades, ...

The Model S2065 notch filter targets noise-reduction applications in the television broadcast band (channels 62 to 68). Its specifications make it an excellent choice for solving difficult ...