Researchers have developed a new method for the accurate determination of the water content of water-soluble compounds. This plays a significant role in various areas, including determining drug ...

Determining aqueous compound solubility has become an essential tool in the early stages of the drug discovery process. Solubility of a compound is important in the Biopharmaceutics Classification ...

Poor solubility remains a big issue for drug development and, as such, is driving innovation in approaches and use of novel technologies to help overcome the associated challenges. Increasingly, ...

Dedong Wu, senior scientist at AstraZeneca, explains how nanoparticle engineering and crystal engineering can aid solubility. Wu: For poorly soluble drug candidates, various enabling techniques have ...

Sucralose, a widely used artificial sweetener sold under the trade name Splenda®, is metabolized in the gut, producing at least two fat-soluble compounds, according to a recent study using rats. The ...

When no more solute can be dissolved in a solvent the solution is said to be saturated. Each different substance has a different solubility. This table shows the solubility of substances in water at ...

Most of the enzymes involved in drug metabolism are present in the liver. This means the liver plays a key role in drug metabolism. Drug metabolism occurs when the body chemically alters drugs so it ...