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In biochemistry, the Lineweaver–Burk plot (or double reciprocal plot) is a graphical representation of the Michaelis–Menten equation of enzyme kinetics, described by Hans Lineweaver and Dean Burk in 1934.

A Lineweaver-Burk plot, sometimes called a double-reciprocal plot, is a method of displaying enzyme kinetics data.

Jun 29, 2025 · The Lineweaver–Burk plot was widely used to determine important terms in enzyme kinetics, such as K m and V m a x, before the wide availability of powerful computers and non-linear …

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May 27, 2025 · The Lineweaver-Burk plot is a simple but powerful tool to study enzymes. By changing a curve into a straight line, it helps scientists find important enzyme features like Km and Vmax more …

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Hans Lineweaver (December 25, 1907 – June 10, 2009) was an American physical chemist, who is credited with introducing the double-reciprocal plot or Lineweaver–Burk plot. [2]

The Lineweaver-Burk plot is the most commonly used linear plot for enzyme kinetic analysis (Figure 2). Today enzyme kinetic constants are determined by fitting experimental data to rate equations by …

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